Pegylated liposomal doxorubicin is active in Stewart–Treves syndrome
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چکیده
منابع مشابه
Pegylated liposomal doxorubicin in ovarian cancer
The encapsulation of doxorubicin in a pegylated liposomal matrix led to a reformulated agent with a different toxicity profile and improved clinical utility. Liposomal doxorubicin is devoid of the cardiac toxicity associated with doxorubicin, but is associated with predictable muco-cutaneous toxicity. The liposomal formulation leads to improved delivery to the target tumor tissue, allowing enha...
متن کاملPegylated liposomal doxorubicin in ovarian cancer
Pegylated liposomal doxorubicin is a formulation of doxorubicin in which the molecule itself is packaged in a liposome made of various lipids with an outer coating of polyethylene glycol. Liposomal technology is being used in increasing amounts in the therapy of a variety of cancers, including ovarian cancers. This article reviews the mechanistic actions of this formulation, the Phase II and Ph...
متن کاملPegylated liposomal doxorubicin in the management of ovarian cancer
Among the pharmaceutical options available for treatment of ovarian cancer, much attention has been progressively focused on pegylated liposomal doxorubicin (PLD), whose unique formulation, which entraps conventional doxorubicin in a bilayer lipidic sphere surrounded by a polyethylene glycol layer, prolongs the persistence of the drug in the circulation and potentiates intratumor drug accumulat...
متن کاملPegylated liposomal-encapsulated doxorubicin in cutaneous composite lymphoma
BACKGROUND Cutaneous composite lymphomas are very rare. Their treatment depends upon the different contributing lymphoma entities. Peripheral T-cell lymphoma, not otherwise specified, (PTCL-NOS) represents an aggressive lymphoma subtype. Follicular cutaneous B-cell lymphoma (FCBCL) runs an indolent course. Treatment with pegylated liposomal encapsulated doxorubicin (PLE-DOXO) has yet not been r...
متن کاملPegylated liposomal doxorubicin in the treatment of mycosis fungoides.
Sir, Mycosis fungoides (MF) is the most common cutaneous T-cell lymphoma. It typically evolves from the early patch and plaque stage to the cutaneous nodular or tumour stage and sometimes visceral involvement is seen in the later stage. MF is also present in an erythrodermic variant accompanied by lymphadenopathy and peripheral blood involvement, known as Sézary syndrome (1). A number of differ...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2007
ISSN: 0923-7534
DOI: 10.1093/annonc/mdm113